What is alloClae™? - an alternative to fat grafting and fillers now in Raleigh

alloClae is a natural tissue filler made from purified donor fat. It’s processed to keep important proteins, collagen, and growth factors while removing unwanted cells. This allows it to safely add volume and improve tissue quality without needing fat harvesting or synthetic implants.

Unlike fat transfer, alloClae doesn’t require liposuction. There’s no need to remove fat from your own body. It’s ready to inject right from the package, making the procedure quicker, easier, and less invasive — perfect for patients who are slim or want a simpler option.

Dr. Glenn Lyle uses alloClae for:

• Restoring facial volume (cheeks, temples, under-eyes)
• Smoothing hip dips and body contour irregularities
• Enhancing buttocks and hips without implants
• Minor breast volume restoration
• Improving scars, skin texture, and cellulite appearance
• Correcting volume loss after weight loss ("Ozempic face")

You may be a good candidate if you:

• Want natural-looking volume without surgery
• Have lost volume due to aging or weight changes
• Don’t have enough fat for traditional fat grafting
• Prefer a minimally invasive, office-based treatment
• Are seeking subtle, natural enhancements

During your consultation, Dr. Lyle will assess your goals and recommend if alloClae is right for you.

Most treatments take about 30 to 60 minutes depending on the number of areas treated. Because it’s a minimally invasive procedure performed under local anesthesia, there’s no need for a hospital stay.

Recovery is usually quick and comfortable:

• Mild swelling, bruising, or tenderness may last 1 to 2 weeks.
• Most patients return to normal activities within a few days.
• Dr. Lyle may recommend avoiding heavy exercise for 2 to 3 weeks.

Your full results will gradually appear as swelling goes down and the tissue integrates.

Results can last several years, depending on the area treated and your body's natural healing response. While some volume loss may occur early on, many patients enjoy long-lasting improvements. Touch-up treatments can help maintain optimal results over time.

Yes, alloClae is very safe when performed by an experienced, board-certified plastic surgeon like Dr. Glenn Lyle. The product is:

• Sterilized to eliminate risks of infection
• Processed to remove DNA and cells that could cause reactions
• Biologically compatible with your own tissues

As with any procedure, minor risks like infection, bruising, or asymmetry can occur but are rare.

Potential risks include:

• Mild swelling, bruising, or tenderness
• Small lumps or irregularities (rare)
• Temporary volume loss
• Infection (very rare)
• Allergic or immune reactions (extremely rare)

Choosing an expert surgeon like Dr. Lyle helps minimize these risks and ensures safe, natural outcomes.

Costs vary depending on the amount of product needed and the number of areas treated. After your consultation, Dr. Lyle’s team will provide a detailed quote based on your personalized treatment plan. Payment plans and financing options may be available to help make treatment more affordable.

Yes. alloClae can be safely used in areas that have previously received dermal fillers, autologous fat transfer, or even implants — depending on the patient’s individual anatomy and surgical history. It’s often used to correct residual asymmetry or volume depletion after these procedures. However, treatment planning requires careful evaluation to avoid overcorrection or product migration.

alloClae is not a permanent filler, but it provides longer-lasting results than many synthetic injectables. The volume enhancement tends to last for several years in many cases, with added benefit from tissue regeneration and collagen support. Some patients may need occasional touch-ups to maintain ideal results, especially in high-movement areas like the face.

While both alloClae and Renuva are allogeneic adipose-derived fillers, they differ in composition, preparation, and indications. alloClae contains a structural matrix as well as cells that provides more robust volume and is suitable for both facial and larger body-area contouring. It also comes in larger volumes (12.5 cc and 25 cc), making it more appropriate for hip dips, buttocks, and breast contouring, whereas Renuva is typically used for smaller facial or scar areas.

When injected properly by an experienced plastic surgeon, alloClae typically integrates smoothly into the surrounding tissues and feels soft and natural. In areas with thin skin or significant movement (like the under-eye area), careful placement is critical to avoid visible or palpable irregularities. Any mild firmness usually softens over time as the tissue heals and remodels.

Yes, one of the most popular off-label uses of alloClae is non-surgical correction of hip dips or mild gluteal hollowing — particularly for patients who are too lean for Brazilian Butt Lift (BBL) surgery or prefer a non-surgical alternative. Because it’s donor-derived, there’s no need to harvest fat through liposuction, and the result is a smooth, natural curve. Volume requirements vary, and multiple sessions may be recommended for optimal shaping.

alloClae is gradually remodeled by your body. Its structural matrix acts as a scaffold that encourages your own tissue to grow into the treated area. Over time, some of the initial volume may resorb, but what remains tends to be your own naturally regenerated tissue. This process contributes to the longevity and softness of the final result.

Yes. In addition to volume restoration, alloClae appears to stimulate tissue remodeling and support collagen production. Patients with mild cellulite, crepey skin, or post-surgical contour irregularities (like tethered scars or liposuction defects) may see smoother, firmer skin over time. While it’s not a skin tightening treatment per se, it often improves texture in the treated area.

For patients who’ve experienced significant volume loss after semaglutide (Ozempic or Wegovy) use, alloClae may be used once weight has stabilized and any acute facial changes have plateaued — typically 3 to 6 months after medication adjustment. In cases of rapid or ongoing weight loss, waiting allows for more predictable results and reduces the chance of needing revisions later.

Yes, but timing matters. Treatments such as RF microneedling, laser resurfacing, or ultrasound-based skin tightening should be performed either before alloClae is injected, or several weeks after the product has stabilized in the tissue. Dr. Lyle will advise on the appropriate sequencing to avoid disrupting integration and ensure optimal healing.

The risk of fat necrosis is significantly lower than with autologous fat grafting, since alloClae contains no living fat cells that require a blood supply. It is primarily a matrix for integration rather than a cellular transplant. However, as with any volume augmentation, minor nodularity or firmness is possible in areas where product pools or healing is uneven. Proper technique and post-care minimize this risk.

Here are general estimates based on common procedures, though exact amounts depend on your anatomy and goals:

• Under-eye hollows: 2–4 cc total
• Cheeks or temples: 5–10 cc per side
• Hip dips: 15–25 cc per side
• Gluteal hollowing or reshaping: 25–50 cc per side
• Breast contour smoothing (not augmentation): 10–20 cc per side

Multiple sessions may be planned for larger-volume areas or subtle layer-building.

As of now, alloClae is an FDA-regulated human tissue product, governed under HCT/P (Human Cell and Tissue Product) guidelines for homologous use. It is not classified as a drug or device and is processed according to FDA tissue banking regulations. Dr. Lyle ensures the product is sourced from a compliant, high-standard laboratory provider.

You can resume light activity within a day or two after treatment. Most patients return to work quickly. Dr. Lyle recommends waiting 2 weeks before high-impact workouts or long-haul flights, especially if large-volume areas were treated. Gentle movement and hydration support healthy healing during the early integration phase.

That depends on your aesthetic goals and how your body responds. In facial treatments, one session may be enough. For body contouring, especially in the hips or buttocks, a staged approach may be needed to build volume gradually. Dr. Lyle will guide you through a customized treatment plan based on your expectations and tissue response.

Booking your consultation is easy!

• Call our office at 984-367-1110
• Visit https://drglennlyle.com/contact-us to request an appointment online
• Located conveniently in Raleigh, NC, serving Cary, Durham, and surrounding communities

Take the first step toward natural, beautiful volume restoration today!